Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication
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منابع مشابه
Global synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of viral replication, including transcription, splicing, nuclear export, translation, packaging and reverse transcription. Nonetheless, chemical probing and other approaches suggest that the HIV-1 genome may contain many more RNA secondary structures of unknown importance and function. To determine wh...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2018
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1006824